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The Stanford ChEM-H Medicinal Chemistry Knowledge Center (MCKC) is located in the Stanford ChEM-H Building. The Knowledge Centers are co-located and consists of over 2,500 sq feet of laboratory space, an open plan office area for up to 10 graduates students/postdocs or staff as well as a lounge area for meetings with collaborators. The MCKC space consists of 10 synthetic chemistry fume hoods equipped with standard synthesis.
Equipment
- Biotage Selekt automated flash chromatography purification systems
- Biotage Initiator microwave synthesizer.
- Biotage V-10 rapid evaporation system.
- Büchi R-300 Rotary evaporators.
- Agilent iQ LCMS.
- Brucker Neo-500 NMR instrument.
ADME
The MCKC is able to perform microsomal stability and permeability assays for our collaborators as well as organize additional in vitro and in vivo testing through partner Contract Research Organizations.
Specialist software
- Dotmatics drug discovery platform to capture, query and visualize data.
- Schrödinger’s Maestro platform.